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ThreatLocker Zero Trust Platform vs Trellix Advanced Threat Defense comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Mar 17, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

ThreatLocker Zero Trust Pla...
Ranking in Advanced Threat Protection (ATP)
5th
Average Rating
9.2
Reviews Sentiment
7.0
Number of Reviews
103
Ranking in other categories
Network Access Control (NAC) (3rd), Endpoint Protection Platform (EPP) (5th), Application Control (1st), ZTNA as a Service (5th), ZTNA (6th), Ransomware Protection (1st)
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
22nd
Average Rating
7.8
Reviews Sentiment
5.6
Number of Reviews
9
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of October 2026, in the Advanced Threat Protection (ATP) category, the mindshare of ThreatLocker Zero Trust Platform is 2.8%, up from 2.4% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 2.1%, up from 1.6% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Mindshare Distribution
ProductMindshare (%)
ThreatLocker Zero Trust Platform2.8%
Trellix Advanced Threat Defense2.1%
Other95.1%
Advanced Threat Protection (ATP)
 

Featured Reviews

Santo Joy - PeerSpot reviewer
Head Of Cyber Security at a outsourcing company with 201-500 employees
Security controls have been strengthened with granular application, ringfencing, and access policies
The features of ThreatLocker Zero Trust Endpoint Protection Platform that I like the most are the Ringfencing, elevation control, storage control, and application whitelisting functionality. For examples of how these features benefit my company, we were looking for a solution across various vendors to actually implement application whitelisting controls. ThreatLocker's agent, which is very lightweight and does not use much CPU or RAM, helped us achieve that solution. Ringfencing was an add-on that ticked off a lot of Australian framework security controls, which is the reason we chose it. My impression of the allowlisting feature in terms of managing which software, scripts, and libraries run on my devices is that ThreatLocker's community page has a lot of information around this, which is very helpful. Not only that, the Cyber Hero support that ThreatLocker provides gives us insights and best practices, helping us achieve that solution and guiding us to the right platform. The impact of Ringfencing on controlling the behavior of approved applications has been a big winner for us because it is something that many other platforms do not provide as a functionality. Having that allowed us to identify what applications talk to each other, which is something that many other platforms do not do. The network control feature impacts my ability to manage network traffic across my endpoints and servers. We have not used this widely across all our partners, but wherever required, we use it. It has been an easy solution for those customers to get that control implemented. The elevation feature's role in facilitating just-in-time administrative access for approved applications shows that elevation control helps in many use cases involving remote control platforms, door usage, and security system platforms that require local admins. There are many solutions that provide this functionality, but the licensing cost seems to be expensive, and it also adds another solution into the mix. Rather than doing that, we try to use ThreatLocker Zero Trust Endpoint Protection Platform to achieve that control. Regarding the storage control feature, I have used it. The primary function is USB blocking, which is very widely adopted, and also just locking down and allowing certain users to access certain file locations helps us there. When it comes to enforcing policy-driven access over various storage devices, it depends on the business risk adapted by the companies that we support, but generally the use case is USB and external storage devices where companies know that is a risk, but they do not have appropriate solutions. There are EDR platforms that claim to do this, but ThreatLocker Zero Trust Endpoint Protection Platform does it at an advanced level. My assessment of the efficiency of the real-time threat intelligence and category controls employed by Web Control in blocking malicious and non-compliant sites leads me to think that Web Control is another functionality within ThreatLocker Zero Trust Endpoint Protection Platform that is an add-on on top of the current set. That is another solution that we use based on what is required for the company, but again, that is not widely adapted yet for our partners.
PP
RSSI at SDIS49
Ensuring long-term reliability while seeking internal email management enhancements
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it's a cloud product, so we don't really know the version as it's always updated. We have not had any problem, but it's difficult to report on what's going on because some days they can wash out perhaps 100 mails, and then it's difficult to say how many attacks you have reached. The right email has been washed out and then nobody has complained. We do not use the Threat Visualization feature; as we are in MX, the mail is washed out before it is in the mail inbox of the user, thus avoiding any problem requiring a reservation. In fact, there is no integration with existing security frameworks. The only problem we can have is that as we have no API interface, there is no inspection of internal mail. I rate Trellix Advanced Threat Defense a nine out of ten.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Overall, ThreatLocker Zero Trust Endpoint Protection Platform has significantly strengthened our endpoint security by enforcing zero trust principles while maintaining operational flexibility and user productivity."
"With ThreatLocker, we don't have shadow IT, and it has reduced ransomware."
"ThreatLocker Zero Trust Platform has impacted our organization positively because our clients are more secure and this is one of the security stacks we offer to our clients so that they feel more secure and we are more in control of what they can do."
"I would rate it a ten out of ten."
"The particular features that stand out for me are the easy management of policies, the speed of threat detection, and the fast allow listing compared to other tools."
"The Zero Trust factor is valuable because it blocks everything. That helps us to stay ahead of bad actors. We do not have to be in recovery mode."
"Blocking is done comprehensively."
"It's easy to use in regards to reducing attack surfaces."
"The fact that in 10 years, we have had no problem is the most valuable feature for us; it's really a washing machine, but the only problem we face is that it's difficult to report on this product."
"The features I find most valuable are: the management, the ability for automatic remediation of threats and it can successfully detect a threat, and to act upon it."
"It is stable and reliable."
"The product is expensive, but it is better than the rest of them in the industry."
"This solution is very easy to use and requires little to no training."
"Its greatest strength is the DXL client which can rapidly disseminate attack information to all clients via the McAfee Agent instead of going through the ePO server."
"It was easy to set up initially."
"Provides good exfiltration, and is an all-in-one product."
 

Cons

"From a reporting perspective, enhancing the ability to customize reports would be beneficial."
"I think one point that could be improved is the maintenance window."
"It has not reduced helpdesk tickets. It has probably increased them by blocking applications and doing its job, resulting in people raising more tickets to know why they cannot use certain things."
"There are some times when applications get submitted, the hashes don't really line up."
"I would suggest further developing the Web Control aspect of ThreatLocker Zero Trust Endpoint Protection Platform and also having better compatibility with Apple devices and mobile devices."
"Efficiency-wise, it was a bit harder in the beginning because we were new to the product and it was a lot of overhead to manage it."
"ThreatLocker Zero Trust Endpoint Protection Platform can be improved by exploring ways of ensuring it is deployed deeper in the device rather than through an extension on the browser and finding ways to integrate all browsers."
"ThreatLocker would benefit from incorporating an antivirus feature or comprehensive 24-hour log monitoring, a valuable enhancement for both business and enterprise-level users."
"It was not complex, but there are things to look out for, because it's an intense product. It scans intensely and there are major obstacles to overcome if it scans while users are using a network, then it is not a good thing."
"There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client."
"This product does the job, but it is not flexible enough to do new environments yet."
"The support on their side is not readily available. It takes a while."
"Make the ATD system a part of the whole product and take the whole thing onto the cloud. While it is there already, it is not to the same level as the on-premise version."
"I would like to see future versions of the solution incorporate artificial intelligence technology."
"We'd like them to be better at dealing with script threats."
"Some of our customers have mentioned the lack of a tool that would allow for remote capabilities without being attached to the internet."
 

Pricing and Cost Advice

"ThreatLocker's pricing seems justifiable."
"Its price is fair. They have added some additional things to it beyond allowlisting. They are up-charging for them, but in terms of the value we get and the way it impacts us, we get a bang for our buck with ThreatLocker than a lot of our other security tools."
"I find ThreatLocker's pricing to be reasonable for the services it provides."
"We have not had any real issues with the pricing. As they have added more features, due to the way our contracts are structured with our customers, we have had to hold off on adopting the new features because they do add costs."
"Others say ThreatLocker is too expensive, and I tell them they're dreaming. It's well-priced for what it does."
"Although the pricing seems good, there have been inconsistencies in contract negotiations."
"I do not know about the licensing and price as it comes bundled from our MSP. However, it seems fairly reasonable for us, which is why we chose it."
"So far, it has been great. I have no complaints. Of course, everybody wishes it was cheaper."
"Our licensing fees for this solution are approximately one million dollars per year."
"The product is expensive, but it is better than the rest of them in the industry."
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Top Industries

By visitors reading reviews
Manufacturing Company
13%
Financial Services Firm
12%
Computer Software Company
9%
Outsourcing Company
9%
Construction Company
16%
Outsourcing Company
16%
Financial Services Firm
12%
Manufacturing Company
9%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business70
Midsize Enterprise19
Large Enterprise21
By reviewers
Company SizeCount
Small Business3
Midsize Enterprise4
Large Enterprise5
 

Questions from the Community

What is your experience regarding pricing and costs for ThreatLocker Allowlisting?
Regarding my experience with pricing, setup cost, and licensing, I remember reaching out to them and it was about over a month. I reached out to them directly and also a couple third-party service ...
What needs improvement with ThreatLocker Allowlisting?
I would like to see ThreatLocker Zero Trust Platform improve by developing some sort of software deployment plan where we can use it for pushing out and installing software onto the computers throu...
What is your primary use case for ThreatLocker Allowlisting?
My main use case for ThreatLocker Zero Trust Platform is allow listing software, as well as Elevation Control and Storage Control. For a specific example of how I use allow listing or Elevation Con...
What needs improvement with McAfee Advanced Threat Defense?
I would like to see an API interface for internal email and control of outgoing email to make it closer to 10. It's necessary; today we have an MX interface, and it would be interesting to have an ...
What is your primary use case for McAfee Advanced Threat Defense?
We are working with Palo Alto products, specifically firewalls. We are only using Palo Alto Firewalls and not Cortex. With FireEye and Trellix, we only work with ETP now because the NDR function wh...
What advice do you have for others considering McAfee Advanced Threat Defense?
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it'...
 

Also Known As

Protect, Allowlisting, Network Control, Ringfencing
McAfee Advanced Threat Defense
 

Overview

 

Sample Customers

Information Not Available
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about ThreatLocker Zero Trust Platform vs. Trellix Advanced Threat Defense and other solutions. Updated: September 2026.
917,433 professionals have used our research since 2012.